Dr. Manjari Kiran
School of Life Sciences, University of Hyderabad (P.O. Central University)
I am interested in applying computational approaches in understanding biology and human disease. I received my PhD training at CDFD Hyderabad during where I defined a novel dichotomy of hubs in human protein interaction networks. I also constructed a drug-target interaction network explaining the relation between side effects of drugs due to specific position of their targets in tissue specific interactions. During my post doctoral training, I used machine learning approaches for defining prognostic set of long non coding RNAs to predict outcome in glioma patients. Additionally, I used publicly available as well as in house generated RNA sequencing data to formulate hypothesis and validate findings for various biological problems.
In my current position at Hyderabad University, I intend to use my computational skills in addressing the role of long non-coding RNAs in cancers. I am also looking at the possibility of integrating interaction networks and NGS data to facilitate diagnosis and treatment regimens of cancer patients.
My immediate interest lies in